(19)
(11) EP 1 144 673 A1

(12)

(43) Date of publication:
17.10.2001 Bulletin 2001/42

(21) Application number: 00905651.6

(22) Date of filing: 19.01.2000
(51) International Patent Classification (IPC)7C12Q 1/00, C12N 15/00, G01N 33/00, A01K 67/00
(86) International application number:
PCT/US0001/205
(87) International publication number:
WO 0042/211 (20.07.2000 Gazette 2000/29)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 19.01.1999 US 116300 P
04.06.1999 US 137620 P
27.07.1999 US 146309 P

(71) Applicant: GLAXO GROUP LIMITED
Greenford, Middlesex UB6 ONN (GB)

(72) Inventor:
  • LENHARD, James, Martin
    Raleigh, NC 27605 (US)

(74) Representative: Crawley, Karen Anne et al
GlaxoSmithKlineCorporate Intellectual PropertyTwo New Horizons Court
Brentford, Middlesex TW8 9EP
Brentford, Middlesex TW8 9EP (GB)

   


(54) METHODS OF SCREENING PROTEASE INHIBITORS, OF INDUCING MICE SUSCEPTIBLE TO HIV PROTEASE INHIBITOR-INDUCED DYSLIPIDEMIA, AND GENES ASSOCIATED THEREWITH