(19)

(11)

EP 1 146 883 A1

(12)

(43) Date of publication: 24.10.2001 Bulletin 2001/43 (21) Application number: 99968159.6 (22) Date of filing: 20.12.1999

(51) International Patent Classification (IPC)7: A61K 31/70, C07H 19/052 (86) International application number: PCT/US9930/490 (87) International publication number: WO 0044/388 (03.08.2000 Gazette 2000/31)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 29.01.1999 US 241367 (71) Applicant: ICN PHARMACEUTICALS Costa Mesa, CA 92626 (US)	(72) Inventor: TAM, Robert Costa Mesa, CA 92626 (US) (74) Representative: Viering, Jentschura & Partner  Postfach 22 14 43 80504 München 80504 München (DE)