(19)
(11) EP 1 147 078 A1

(12)

(43) Date of publication:
24.10.2001 Bulletin 2001/43

(21) Application number: 00904570.9

(22) Date of filing: 27.01.2000
(51) International Patent Classification (IPC)7C07C 311/29, C07F 9/53, A61K 31/18, A61K 31/664, A61P 19/02
(86) International application number:
PCT/US0001/865
(87) International publication number:
WO 0044/711 (03.08.2000 Gazette 2000/31)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 27.01.1999 US 239083

(71) Applicant: American Cyanamid Company
Madison,New Jersey 07940-0874 (US)

(72) Inventors:
  • LEVIN, Jeremy, Ian
    New City, NY 10956 (US)
  • CHEN, James, Ming
    Bedminster, NJ 07921 (US)
  • ZASK, Arie
    New York, NY 10128 (US)

(74) Representative: Wileman, David Francis, Dr. et al
c/o Wyeth LaboratoriesHuntercombe Lane South
TaplowMaidenheadBerkshire SL6 OPH
TaplowMaidenheadBerkshire SL6 OPH (GB)

   


(54) ACETYLENIC (BETA)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS