(19)

(11)

EP 1 147 118 A1

(12)

(43) Date of publication: 24.10.2001 Bulletin 2001/43 (21) Application number: 00906899.0 (22) Date of filing: 12.01.2000

(51) International Patent Classification (IPC)7: C07H 1/00, C07H 3/04, C07H 15/00, C07H 17/00, A61K 31/715 (86) International application number: PCT/US0000/686 (87) International publication number: WO 0042/052 (20.07.2000 Gazette 2000/29)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 12.01.1999 US 115595 P (71) Applicant: Princeton University Princeton, NJ 08544-0036 (US)	(72) Inventors: KAHNE, Daniel Princeton, NJ 08540 (US) GE, Min Princeton, NJ 08540 (US) (74) Representative: Luderschmidt, Schüler & Partner GbR  Patentanwälte,John-F.-Kennedy-Strasse 4 65189 Wiesbaden 65189 Wiesbaden (DE)