(19)

(11)

EP 1 147 189 A2

(12)

(88) Date of publication A3: 16.11.2000 (43) Date of publication: 24.10.2001 Bulletin 2001/43 (21) Application number: 99968074.7 (22) Date of filing: 06.12.1999

(51) International Patent Classification (IPC)7: C12N 15/11, C12N 9/00, C12N 15/86, A61K 48/00, A61K 31/70 (86) International application number: PCT/US9928/772 (87) International publication number: WO 0032/765 (08.06.2000 Gazette 2000/23)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 04.12.1998 US 110954 P (71) Applicant: IMMUSOL, INC. San Diego, CA 92121 (US)	(72) Inventors: TRITZ, Richard San Diego, CA 92121 (US) WELCH, Peter, J. San Diego, CA 92116 (US) BARBER, Jack, R. San Diego, CA 92128 (US) ROBBINS, Joan, M. San Diego, CA 92131 (US) (74) Representative: Gowshall, Jonathan Vallance et al FORRESTER & BOEHMERT,Franz-Joseph Strasse 38 80801 München 80801 München (DE)