(19)
(11) EP 1 147 202 A2

(12)

(88) Date of publication A3:
21.12.2000

(43) Date of publication:
24.10.2001 Bulletin 2001/43

(21) Application number: 00908395.7

(22) Date of filing: 26.01.2000
(51) International Patent Classification (IPC)7C12N 15/57, A61K 38/48, C12N 9/68, A61K 48/00
(86) International application number:
PCT/US0002/091
(87) International publication number:
WO 0044/391 (03.08.2000 Gazette 2000/31)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 28.01.1999 US 117617 P
09.08.1999 US 370719

(71) Applicant: The Children's Medical Center Corporation
Boston, Massachusetts 02115 (US)

(72) Inventors:
  • SHING, Yuen, W.
    Randolph, MA 02368 (US)
  • O'REILLY, Michael, S.
    Winchester, MA 01890 (US)
  • FOLKMAN, M., Judah
    Brookline, MA 02146 (US)

(74) Representative: Touati, Catherine 
Cabinet Plasseraud,84, rue d'Amsterdam
75440 Paris Cedex 09
75440 Paris Cedex 09 (FR)

   


(54) PLASMINOGEN KRINGLE 4 REGION FRAGMENTS AND METHODS OF USE