(19)

(11)

EP 1 151 084 A2

(12)

(88) Date of publication A3: 08.03.2001 (43) Date of publication: 07.11.2001 Bulletin 2001/45 (21) Application number: 00911722.7 (22) Date of filing: 08.02.2000

(51) International Patent Classification (IPC)7: C12N 9/02, C12N 15/53, A01H 5/00, C12N 15/82, G01N 33/50, C12N 15/10, C12Q 1/68 (86) International application number: PCT/US0003/176 (87) International publication number: WO 0047/726 (17.08.2000 Gazette 2000/33)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 10.02.1999 US 119590 P (71) Applicant: E.I. DU PONT DE NEMOURS AND COMPANY WilmingtonDelaware 19898 (US)	(72) Inventors: CAHOON, Rebecca, E. Wilmington, DE 19806 (US) FALCO, Saverio, Carl Arden, DE 19810 (US) KINNEY, Anthony, J. Wilmington, DE 19809 (US) MIAO, Guo-Hua Hockessin, DE 19707 (US) (74) Representative: Webber, Philip Michael  Frank B. Dehn & Co.,179 Queen Victoria Street London EC4V 4EL London EC4V 4EL (GB)