(19)
(11) EP 1 151 091 A1

(12)

(43) Date of publication:
07.11.2001 Bulletin 2001/45

(21) Application number: 00910029.8

(22) Date of filing: 31.01.2000
(51) International Patent Classification (IPC)7: C12N 15/00, C12N 5/00, C07H 21/04
(86) International application number:
PCT/US0002/405
(87) International publication number:
WO 0046/360 (10.08.2000 Gazette 2000/32)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 04.02.1999 US 118601 P
08.06.1999 US 138134 P

(71) Applicant: Merck & Co., Inc.
Rahway,New Jersey 07065-0907 (US)

(72) Inventors:
  • BETT, Andrew
    Rahway, NJ 07065-0907 (US)
  • SANDIG, Volker
    Rahway, NJ 07065-0907 (US)
  • YOUIL, Rima
    Rahway, NJ 07065-0907 (US)

(74) Representative: Horgan, James Michael Frederic 
Merck & Co., Inc.,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) IMPROVED HELPER DEPENDENT VECTOR SYSTEM FOR GENE THERAPY