(19)

(11)

EP 1 151 111 A2

(12)

(88) Date of publication A3: 14.12.2000 (43) Date of publication: 07.11.2001 Bulletin 2001/45 (21) Application number: 00910141.1 (22) Date of filing: 09.02.2000

(51) International Patent Classification (IPC)7: C12N 15/54, C12N 15/82, C12N 9/12, C12Q 1/68, C12Q 1/48 (86) International application number: PCT/US0003/513 (87) International publication number: WO 0047/748 (17.08.2000 Gazette 2000/33)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 10.02.1999 US 119588 P (71) Applicant: E.I. DU PONT DE NEMOURS AND COMPANY WilmingtonDelaware 19898 (US)	(72) Inventors: FAMODU, Omolayo, O. Newark, DE 19702 (US) PEARLSTEIN, Richard, W. Newark, DE 19702 (US) (74) Representative: Webber, Philip Michael  Frank B. Dehn & Co.,179 Queen Victoria Street London EC4V 4EL London EC4V 4EL (GB)