(19)

(11)

EP 1 151 271 A1

(12)

(43) Date of publication: 07.11.2001 Bulletin 2001/45 (21) Application number: 00904229.2 (22) Date of filing: 06.01.2000

(51) International Patent Classification (IPC)7: G01N 15/06, G01N 21/00, G01N 21/76, G01N 21/77, G01N 33/531, G01N 33/538, G01N 33/543, G01N 33/551, G01N 33/553, B01D 3/00, B01D 11/00, B01D 35/06, A01N 1/02, B01J 19/08, B01L 3/00, B01L 11/00, C12M 1/00, C12M 1/40 (86) International application number: PCT/US0000/274 (87) International publication number: WO 0040/947 (13.07.2000 Gazette 2000/28)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 06.01.1999 US 114843 P (71) Applicant: University of Medicine and Dentistry of New Jersey New Brunswick, NJ08903-2688 (US)	(72) Inventors: SCIORRA, Leonard Neshanic Station, NJ 08853 (US) ZIMNOCH, Joseph Sellersville, PA 18960-2742 (US) (74) Representative: Watson, Robert James et al Mewburn EllisYork House23 Kingsway London WC2B 6HP London WC2B 6HP (GB)