(19)

(11)

EP 1 152 747 A2

(12)

(88) Date of publication A3: 11.01.2001 (43) Date of publication: 14.11.2001 Bulletin 2001/46 (21) Application number: 00914614.3 (22) Date of filing: 17.02.2000

(51) International Patent Classification (IPC)7: A61K 7/48 (86) International application number: PCT/US0004/082 (87) International publication number: WO 0048/555 (24.08.2000 Gazette 2000/34)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 19.02.1999 EP 99039257 (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati,Ohio 45202 (US)	(72) Inventors: BELL, Michael, David Crowthorne,Berkshire RG45 7QS (GB) ROLLS, Richard, George, Albert Feltham TW14 9DD (GB) ELLIOTT, Russell, Philip Egham,Surrey TW20 9RJ (GB) DUKE, Roland, Philip Wokingham,Berks RG41 3NB (GB) (74) Representative: Wilding, Richard Alan  Procter & Gamble Technical Centers Ltd.Lovett HouseLovett Rd. Staines,Middlesex TW18 3ZA Staines,Middlesex TW18 3ZA (GB)