(19)
(11)
EP 1 152 752 A1
(12)
(43)
Date of publication:
14.11.2001
Bulletin 2001/46
(21)
Application number:
00907060.8
(22)
Date of filing:
27.01.2000
(51)
International Patent Classification (IPC)
7
:
A61K
31/00
,
C07K
16/28
,
C07K
14/52
(86)
International application number:
PCT/US0002/123
(87)
International publication number:
WO 0044/365
(
03.08.2000
Gazette 2000/31)
(84)
Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI
(30)
Priority:
29.01.1999
US 239283
(71)
Applicant:
Millennium Pharmaceuticals, Inc.
Cambridge,Massachusetts 02139 (US)
(72)
Inventor:
HANCOCK, Wayne, W.
Medfield, MA 02052 (US)
(74)
Representative:
Holdcroft, James Gerald, Dr.
Graham Watt & Co.,Riverhead
Sevenoaks, Kent TN13 2BN
Sevenoaks, Kent TN13 2BN (GB)
(54)
METHODS FOR PREVENTING GRAFT REJECTION AND ISCHEMIA-REPERFUSION INJURY