(19)

(11)

EP 1 153 126 A1

(12)

(43) Date of publication: 14.11.2001 Bulletin 2001/46 (21) Application number: 00903629.4 (22) Date of filing: 25.01.2000

(51) International Patent Classification (IPC)7: C12N 15/00, C07K 14/22, C07K 16/12 (86) International application number: PCT/EP0000/560 (87) International publication number: WO 0044/890 (03.08.2000 Gazette 2000/31)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 29.01.1999 GB 9902084 (71) Applicant: SmithKline Beecham Biologicals s.a. 1330 Rixensart (BE)	(72) Inventor: THONNARD, Joelle 1330 Rixensart (BE) (74) Representative: Mallalieu, Catherine Louise et al D. Young & Co.,21 New Fetter Lane London EC4A 1DA London EC4A 1DA (GB)