(19)
(11) EP 1 155 010 A1

(12)

(43) Date of publication:
21.11.2001 Bulletin 2001/47

(21) Application number: 00903848.0

(22) Date of filing: 16.02.2000
(51) International Patent Classification (IPC)7C07D 307/54, A61K 31/335, A61K 31/38, A61K 31/275, C07D 213/57, C07D 333/24, C07D 409/12, C07C 255/29, C07D 231/18, C07D 513/04, C07D 409/04, C07D 233/84, A61P 3/14
// C07D513:04, C07D277:00
(86) International application number:
PCT/GB0000/532
(87) International publication number:
WO 0049/007 (24.08.2000 Gazette 2000/34)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 20.02.1999 GB 9903857
10.07.1999 GB 9916098

(71) Applicant: AstraZeneca AB
151 85 Södertälje (SE)

(72) Inventors:
  • TUCKER, Howard
    Macclesfield,Cheshire SK10 4TG (GB)
  • LARGE, Michael, Stewart
    Macclesfield,Cheshire SK10 4TG (GB)
  • OLDFIELD, John
    Macclesfield,Cheshire SK10 4TG (GB)
  • JOHNSTONE, Craig
    Macclesfield,Cheshire SK10 4TG (GB)
  • EDWARDS, Philip, Neil
    Macclesfield,Cheshire SK10 4TG (GB)

(74) Representative: Tierney, Francis John et al
AstraZeneca UK Limited,Global Intellectual Property Patents,P.O. Box 272,Mereside,Alderley Park
Macclesfield,Cheshire SK10 4GR
Macclesfield,Cheshire SK10 4GR (GB)

   


(54) ACETAMIDO ACETONITRILE DERIVATIVES AS INHIBITORS OF CATHEPSIN L AND/OR CATHEPSIN S