PROCESS FOR PREPARING A STABLE NON-HYGROSCOPIC CRYSTALLINE N-[N-[N-(PIPERDIN-4-YL)BUTANOYL)-N-ETHYLGLYCYL]-(L)-ASPARTYL]-SS-CYCLOHEXYLALANINE AMIDE - Patent 1155033

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EP 1 155 033 A1

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(43)	Date of publication:
	21.11.2001 Bulletin 2001/47

(21)	Application number: 99969282.5

(22)	Date of filing: 15.12.1999

(51)	International Patent Classification (IPC)⁷: C07K 5/08, C07K 5/02, C07C 227/42, C07D 213/78

(86)	International application number:
	PCT/US9929/969

(87)	International publication number:
	WO 0040/601 (13.07.2000 Gazette 2000/28)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

30.12.1998 US 114289 P

(71)	Applicant: Aventis Pharmaceuticals Products Inc.
	Bridgewater, NJ 08807-0800 (US)

(72)	Inventors:
	AUTHELIN, Jean, Rene F-91180 Saint Germain les Arpajon (FR) THOUZERY, Alain F-91600 Savigny sur Orge (FR) MANGIN, Fabrice F-75018 Paris (FR) BAILLY, Pierre F-95470 Fosses (FR)

(74)	Representative: Jones, Stephen Anthony
	AdamsonJonesBroadway Business Centre32a Stoney Street Nottingham NG1 1LL Nottingham NG1 1LL (GB)

(54)	PROCESS FOR PREPARING A STABLE NON-HYGROSCOPIC CRYSTALLINE N-[N-[N-(PIPERDIN-4-YL)BUTANOYL)-N-ETHYLGLYCYL]-(L)-ASPARTYL]-SS-CYCLOHEXYLALANINE AMIDE