(19)

(11)

EP 1 155 043 A1

(12)

(43) Date of publication: 21.11.2001 Bulletin 2001/47 (21) Application number: 00991302.1 (22) Date of filing: 20.12.2000

(51) International Patent Classification (IPC)7: C08B 37/16, A61K 47/48, A23L 1/0522 (86) International application number: PCT/IB0002/060 (87) International publication number: WO 0148/024 (05.07.2001 Gazette 2001/27)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR (30) Priority: 23.12.1999 US 172099 P 11.10.2000 US 686695 (71) Applicant: CERESTAR HOLDING B.V. NL-4551 LA Sas van Gent (NL)	(72) Inventors: XU, Ansui Carmel, IN 46033 (US) QI, Helena Munster, IN 46321 (US) SHIEH, Wen Munster, IN 46321 (US) (74) Representative: Wilkinson, Stephen John  Stevens, Hewlett & Perkins1 St. Augustine's Place Bristol BS1 4UD Bristol BS1 4UD (GB)