(19)
(11) EP 1 156 824 A2

(12)

(88) Date of publication A3:
25.01.2001

(43) Date of publication:
28.11.2001 Bulletin 2001/48

(21) Application number: 00912209.4

(22) Date of filing: 10.03.2000
(51) International Patent Classification (IPC)7A61K 39/00, A61P 35/00
// C07K14/50, C07K14/52
(86) International application number:
PCT/US0006/320
(87) International publication number:
WO 0053/219 (14.09.2000 Gazette 2000/37)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 11.03.1999 US 266543

(71) Applicant: EntreMed, Inc.
Rockville, MD 20850 (US)

(72) Inventors:
  • HOLADAY, John, W.
    Bethesda, MD 20817 (US)
  • RUIZ, Antonio
    Gaithersburg, MD 20878 (US)
  • MADSEN, John
    Knoxville, MD 21758 (US)

(74) Representative: Stevens, Ian Edward 
Eric Potter Clarkson,Park View House,58 The Ropewalk
Nottingham NG1 5DD
Nottingham NG1 5DD (GB)

   


(54) COMPOSITIONS AND METHODS FOR TREATING CANCER AND HYPERPROLIFERATIVE DISORDERS