(19)
(11) EP 1 157 119 A1

(12)

(43) Date of publication:
28.11.2001 Bulletin 2001/48

(21) Application number: 00904136.9

(22) Date of filing: 07.02.2000
(51) International Patent Classification (IPC)7C12N 15/82, C07K 14/415, A01H 5/00
(86) International application number:
PCT/NL0000/075
(87) International publication number:
WO 0046/383 (10.08.2000 Gazette 2000/32)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 05.02.1999 DK 15899
10.02.1999 US 119388 P

(71) Applicant: RIJKSUNIVERSITEIT LEIDEN
2300 RA Leiden (NL)

(72) Inventors:
  • MEMELINK, Johan
    NL-2318 VC Leiden (NL)
  • VAN DER FITS, Cornelia, Theodora, Elisabeth
    NL-2355 DB Hoogmade (NL)
  • MENKE, Franciscus, Leonardus
    NL-3123 NR Schiedam (NL)
  • KIJNE, Jan, Willem
    NL-2311 XV Leiden (NL)

(74) Representative: Jorritsma, Ruurd 
Nederlandsch OctrooibureauScheveningseweg 82P.O. Box 29720
2502 LS The Hague
2502 LS The Hague (NL)

   


(54) METHOD OF MODULATING METABOLITE BIOSYNTHESIS IN RECOMBINANT CELLS