(19)

(11)

EP 1 159 020 A1

(12)

(43) Date of publication: 05.12.2001 Bulletin 2001/49 (21) Application number: 00909231.3 (22) Date of filing: 23.02.2000

(51) International Patent Classification (IPC)7: A61M 11/00, A61M 15/00, A61M 16/00 (86) International application number: PCT/EP0001/443 (87) International publication number: WO 0053/247 (14.09.2000 Gazette 2000/37)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 06.03.1999 GB 9905134 27.07.1999 GB 9917470 (71) Applicant: GLAXO GROUP LIMITED Greenford, Middlesex UB6 ONN (GB)	(72) Inventors: JONES, Anthony, Patrick WareHerts SG12 0DP (GB) ANDERSON, Gregor, John, McLennan WareHerts. SG12 0DP (GB) (74) Representative: Pike, Christopher Gerard  Pike & Co.Hayes Loft68A Hayes Place Marlow, Bucks. SL7 2BT Marlow, Bucks. SL7 2BT (GB)