(19)
(11) EP 1 159 620 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
06.07.2005 Bulletin 2005/27

(45) Mention of the grant of the patent:
11.05.2005 Bulletin 2005/19

(21) Application number: 00907799.1

(22) Date of filing: 03.03.2000
(51) International Patent Classification (IPC)7: G01N 33/68, A61K 45/00, C07K 7/00
(86) International application number:
PCT/GB2000/000785
(87) International publication number:
WO 2000/052478 (08.09.2000 Gazette 2000/36)

(54)

DETECTION OF MTOC DISRUPTING SUBSTANCES

NACHWEIS MTOC VERRENKENDEN SUBSTANZEN

DETECTION DE SUBSTANCES DE RUPTURE D'INTEGRITE DE CENTRE ORGANISANT LES MICROTUBULES

(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 04.03.1999 GB 9905007

(43) Date of publication of application:
05.12.2001 Bulletin 2001/49

(73) Proprietor: Cyclacel Limited
London N1 7JQ (GB)

(72) Inventors:
  • GLOVER, David, Moore
    Sandy, Bedfordshire SG19 3AA (GB)
  • AVIDES, Maria do Carmo
    Cambridge CB3 9HD (GB)

(74) Representative: Nachshen, Neil Jacob et al
D Young & Co 120 Holborn
London EC1N 2DY
London EC1N 2DY (GB)


(56) References cited: : 
WO-A-97/06440
   
  • MEDLINE, Washington DC USA; abstract no. 97296495, whole abstract XP002140154 cited in the application & R.D. SAUNDERS ET AL.: "The Drosophila gene abnormal spindle encodes a novel microtubule-associated protein that associates with the polar regions of the mitotic spindle " JOURNAL OF CELL BIOLOGY, vol. 137, no. 4, 19 May 1997 (1997-05-19), pages 881-890, New York NY USA
  • MEDLINE, Washington DC USA; abstract no. 98120401, abstract lines 14-17 XP002140155 & A BANAN ET AL.: "Protection against ethanol injury by prostaglandin in a human intestinal cell line: role of microtubules " AMERICAN JOURNAL OF PHYSIOLOGY, vol. 274, no. 1 PT 1, 1 January 1998 (1998-01-01), pages G111-G121, St. Loius MI USA
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).