(19)
(11) EP 1 161 279 A1

(12)

(43) Date of publication:
12.12.2001 Bulletin 2001/50

(21) Application number: 00913894.2

(22) Date of filing: 10.03.2000
(51) International Patent Classification (IPC)7A61P 7/02, A61P 9/12, A61K 31/715, A61K 45/06, A61K 38/49, A61K 38/02, A61K 31/42, A61K 31/60
// A61K38:49, A61K31:415, A61K38:02, A61K31:415,(A61K45/06, 31:715), A61K31:415, A61K31:60, A61K31:415, A61K31:42, A61K31:415
(86) International application number:
PCT/US0006/451
(87) International publication number:
WO 0053/264 (14.09.2000 Gazette 2000/37)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
LT LV RO SI

(30) Priority: 11.03.1999 US 123815 P

(71) Applicant: Du Pont Pharmaceuticals Company
Wilmington, DE 19807 (US)

(72) Inventor:
  • WONG, Pancras, C.
    Wilmington, DE 19808 (US)

(74) Representative: Howard, Paul Nicholas et al
Carpmaels & Ransford43 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) TREATMENT OF THROMBOSIS BY COMBINED USE OF A FACTOR XA INHIBITOR AND ASPIRIN, TISSUE PLASMINOGEN ACTIVATOR (TPA), A GPIIB/IIIA ANTAGONIST, LOW MOLECULAR WEIGHT HEPARIN OR HEPARIN