(19)
(11) EP 1 161 551 A2

(12)

(88) Date of publication A3:
15.02.2001

(43) Date of publication:
12.12.2001 Bulletin 2001/50

(21) Application number: 00918144.7

(22) Date of filing: 16.03.2000
(51) International Patent Classification (IPC)7: C12N 15/90, C12N 15/10, C12N 9/22
(86) International application number:
PCT/US0007/317
(87) International publication number:
WO 0055/346 (21.09.2000 Gazette 2000/38)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 17.03.1999 US 270620

(71) Applicant: Paradigm Genetics Inc.
Research Triangle Park, NC 27709-4528 (US)

(72) Inventors:
  • HAMER, John, E.
    Durham, NC 27707 (US)
  • HAMER, Lisbeth
    Durham, NC 27707 (US)

(74) Representative: Griffin, Kenneth David 
Saunders & Dolleymore,9, Rickmansworth Road
Watford,Hertfordshire WD18 0JU
Watford,Hertfordshire WD18 0JU (GB)

   


(54) METHODS AND MATERIALS FOR THE RAPID AND HIGH VOLUME PRODUCTION OF A GENE KNOCK-OUT LIBRARY IN AN ORGANISM