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<SDOBI lang="en"><B000><eptags><B001EP>ATBECHDEDKESFRGBGRITLILUNLSEMCPTIE......FI..........................................................</B001EP><B005EP>J</B005EP><B007EP>DIM360 Ver 2.15 (14 Jul 2008) -  2999001/0</B007EP></eptags></B000><B100><B110>1162272</B110><B120><B121>CORRECTED EUROPEAN PATENT SPECIFICATION</B121></B120><B130>B8</B130><B132EP>B1</B132EP><B140><date>20091021</date></B140><B150><B151>W1</B151><B153>54</B153><B155><B1551>de</B1551><B1552>Bibliographie</B1552><B1551>en</B1551><B1552>Bibliography</B1552><B1551>fr</B1551><B1552>Bibliographie</B1552></B155></B150><B190>EP</B190></B100><B200><B210>01113517.5</B210><B220><date>19960626</date></B220><B240><B241><date>20050110</date></B241><B242><date>20060407</date></B242></B240><B250>en</B250><B251EP>en</B251EP><B260>en</B260></B200><B300><B310>500306</B310><B320><date>19950710</date></B320><B330><ctry>US</ctry></B330></B300><B400><B405><date>20091021</date><bnum>200943</bnum></B405><B430><date>20011212</date><bnum>200150</bnum></B430><B450><date>20081105</date><bnum>200845</bnum></B450><B452EP><date>20080408</date></B452EP><B480><date>20091021</date><bnum>200943</bnum></B480></B400><B500><B510EP><classification-ipcr sequence="1"><text>C12N  15/57        20060101AFI20040206BHEP        </text></classification-ipcr><classification-ipcr sequence="2"><text>C12N   9/64        20060101ALI20040206BHEP        </text></classification-ipcr><classification-ipcr sequence="3"><text>C12N  15/86        20060101ALI20040206BHEP        </text></classification-ipcr><classification-ipcr sequence="4"><text>C07K  16/30        20060101ALI20040206BHEP        </text></classification-ipcr><classification-ipcr sequence="5"><text>A61K  38/43        20060101ALI20040206BHEP        </text></classification-ipcr></B510EP><B540><B541>de</B541><B542>Herstellung von einer Immunantwort gegen Prostat-spezifisches Antigen (SPA)</B542><B541>en</B541><B542>Generation of immune responses to prostate-specific antigen (SPA)</B542><B541>fr</B541><B542>Génération de réponses immunitaires à l'antigène spécifique de la prostate (SPA)</B542></B540><B560><B561><text>EP-A- 0 652 014</text></B561><B561><text>EP-A- 0 725 139</text></B561><B561><text>WO-A-95/04548</text></B561><B561><text>ZA-A- 9 401 645</text></B561><B562><text>HODGE J W ET AL: "A recombinant vaccinia virus expressing human prostate - specific antigen (PSA): Safety and immunogenicity in a non-human primate." INTERNATIONAL JOURNAL OF CANCER 63 (2). 1995. 231-237. ISSN: 0020-7136, XP000605674</text></B562><B562><text>CORMAN J M ET AL: "Prostate specific antigenic peptides induce T - cell proliferation in-vitro: A model for the development of prostate specific tumor vaccines." NINETY-FIRST ANNUAL MEETING OF THE AMERICAN UROLOGY ASSOCIATION, ORLANDO, FLORIDA, USA, MAY 4-9, 1996. JOURNAL OF UROLOGY 155 (5 SUPPL.). 1996. 528A. ISSN: 0022-5347, XP000604547</text></B562><B562><text>CORRELAE P ET AL: "Generation of human T - cell lines specific for prostate specific antigen using an oligo-epitope peptide." 87TH ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, WASHINGTON, D.C., USA, APRIL 20-24, 1996. PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL MEETING 37 (0). 1996. 488-489. ISSN: 0197-016X, XP002018984</text></B562><B562><text>LU, EDWARD W. ET AL: "Factors affecting production of antibodies to prostate antigens by in vitro-primed human splenocytes" HYBRIDOMA (1993), 12(4), 381-9 CODEN: HYBRDY;ISSN: 0272-457X, 1993, XP000605666</text></B562><B562><text>P. CORREALE ET AL.: "In vitro stimulation of human cytotoxic T lymphocytes specific for peptides derived from prostate specific antigen." 9TH INTERNATIONAL CONGRESS OF IMMUNOLOGY, no. 3449, 1 January 1995 (1995-01-01), page 582, XP000607089</text></B562><B562><text>J. KANTOR ET AL.: "Immunogenicity and safety of a recombinant Vaccinia virus vaccine expressing the carcinoembryonic antigen gene in a nonhuman primate." CANCER RESEARCH, vol. 52, 15 December 1992 (1992-12-15), pages 6917-6925, XP000605381</text></B562><B562><text>ABULAFIA R ET AL: "IN-VITRO PRODUCTION OF T CELLS IMMUNOREACTIVE AGAINST PROSTATE SPECIFIC ANTIGEN A NOVEL APPROACH FOR AN ANTIGEN - SPECIFIC ADOPTIVE IMMUNOTHERAPY PROGRAM FOR PROSTATE CANCER." JOINT MEETING OF THE AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, AND THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS, NEW ORLEANS, LOUISIANA, USA, JUNE 4-7, 1990. FASEB (FED AM SOC EXP BIOL) J 4 (7). 1990. A2021. CODEN: FAJOEC ISSN: 0892-6638, XP002018985</text></B562><B562><text>ROSS S ET AL: "Adoptive immunotherapy of hormone-refractory, stage D2 prostate cancer using ex vivo activated autologous T cells (autolymphocyte therapy): Results from a pilot study." BIOTECHNOLOGY THERAPEUTICS 4 (3-4). 1993. 197-211. ISSN: 0898-2848, XP000605665</text></B562><B562><text>E. PAOLETTI ET AL.: "Immunotherapeutic stategies for cancer using poxvirus vectors." ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 690, 1993, pages 292-300, XP000605669</text></B562><B562><text>J.F. DONOVAN ET AL.: "Immunotherapy of prostate cancer." PROBLEMS IN UROLOGY, vol. 4, no. 3, September 1990 (1990-09), pages 489-505, XP000604543</text></B562><B562><text>KAUFMAN H.L. ET AL: 'Phase II randomized study of vaccine treatment of advanced prostate cancer (E7897): A trial of the Eastern Cooperative Oncology Group.' JOURNAL OF CLINICAL ONCOLOGY vol. 22, no. 11, 01 June 2004, pages 2122 - 2132</text></B562><B562><text>KAUFMAN H.L. ET AL: 'Phase II prime/boost vaccination using poxviruses expressing PSA in hormone dependent prostate cancer: Follow-up clinical results from ECOG 7897' JOURNAL OF CLINICAL ONCOLOGY vol. 23, no. 16S, 01 June 2005, page 4501</text></B562><B562><text>MARSHALL J.L. ET AL: 'Phase I study in cacner patients of a replication-defective avipox recombinant vaccine that expresses human carcinoembryonic antigen.' JOURNAL OF CLINICAL ONCOLOGY vol. 17, no. 1, 1999, pages 332 - 337</text></B562></B560></B500><B600><B620><parent><pdoc><dnum><anum>96923417.8</anum><pnum>0840791</pnum></dnum><date>19970130</date></pdoc></parent></B620></B600><B700><B720><B721><snm>Schlom, Jeffrey
National Cancer Institute</snm><adr><str>10 Center Drive, Bldg 10, Room 8B09</str><city>Bethesda, Maryland 20892</city><ctry>US</ctry></adr></B721><B721><snm>Panicali, Dennis,
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