(19)

(11)

EP 1 162 886 A1

(12)

(43) Date of publication: 19.12.2001 Bulletin 2001/51 (21) Application number: 00910266.6 (22) Date of filing: 22.02.2000

(51) International Patent Classification (IPC)7: A01N 63/00, A61K 38/43, A61K 38/44, A61K 38/54, C12N 5/00, C12N 15/00 (86) International application number: PCT/US0004/438 (87) International publication number: WO 0049/876 (31.08.2000 Gazette 2000/35)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 23.02.1999 US 121418 P (71) Applicant: Bernstein, Eric F. Wynnewood, Pennsylvania 19096 (US)	(72) Inventor: Bernstein, Eric F. Wynnewood, Pennsylvania 19096 (US) (74) Representative: Ablett, Graham Keith et al Ablett & Stebbing, Caparo House, 101-103 Baker Street London W1U 6FQ London W1U 6FQ (GB)