(19)

(11)

EP 1 163 011 A2

(12)

(88) Date of publication A3: 04.10.2001 (43) Date of publication: 19.12.2001 Bulletin 2001/51 (21) Application number: 00916188.6 (22) Date of filing: 09.03.2000

(51) International Patent Classification (IPC)7: A61K 47/48 (86) International application number: PCT/US0006/160 (87) International publication number: WO 0053/231 (14.09.2000 Gazette 2000/37)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 09.03.1999 US 265307 01.03.2000 US 186152 P (71) Applicant: Protarga Inc. Conshohocken, PA 19428 (US)	(72) Inventors: WEBB, Nigel, L. Bryn Mawr, PA 19010 (US) BRADLEY, Matthews, O. Laytonsville, MD 20882 (US) ANTHONY, Forrest Villanova, PA 19085 (US) FISHER, Mark King of Prussia, PA 19406 (US) (74) Representative: Jump, Timothy John Simon et al Venner Shipley & Co. 20 Little Britain London EC1A 7DH London EC1A 7DH (GB)