(19)
(11)
EP 1 163 215 A1
(12)
(43)
Date of publication:
19.12.2001
Bulletin 2001/51
(21)
Application number:
00916525.9
(22)
Date of filing:
15.03.2000
(51)
International Patent Classification (IPC)
7
:
C07C
323/60
,
C07D
213/57
,
C07D
333/24
,
C07D
333/34
,
C07D
207/32
,
C07D
307/54
,
A61K
31/277
,
A61K
31/44
,
A61K
31/381
,
A61K
31/40
,
A61K
31/341
,
A61P
35/00
(86)
International application number:
PCT/US0007/262
(87)
International publication number:
WO 0056/706
(
28.09.2000
Gazette 2000/39)
(84)
Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
LT LV RO SI
(30)
Priority:
19.03.1999
US 125330 P
(71)
Applicant:
Du Pont Pharmaceuticals Company
Wilmington, DE 19807 (US)
(72)
Inventor:
HOBBS, Frank, W.
Wilmington, DE 19803 (US)
(74)
Representative:
Jones, Alan John et al
CARPMAELS & RANSFORD 43 Bloomsbury Square
London, WC1A 2RA
London, WC1A 2RA (GB)
(54)
AMINO-THIO-ACRYLONITRILES AS MEK INHIBITORS