(19)
(11) EP 1 163 215 A1

(12)

(43) Date of publication:
19.12.2001 Bulletin 2001/51

(21) Application number: 00916525.9

(22) Date of filing: 15.03.2000
(51) International Patent Classification (IPC)7C07C 323/60, C07D 213/57, C07D 333/24, C07D 333/34, C07D 207/32, C07D 307/54, A61K 31/277, A61K 31/44, A61K 31/381, A61K 31/40, A61K 31/341, A61P 35/00
(86) International application number:
PCT/US0007/262
(87) International publication number:
WO 0056/706 (28.09.2000 Gazette 2000/39)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
LT LV RO SI

(30) Priority: 19.03.1999 US 125330 P

(71) Applicant: Du Pont Pharmaceuticals Company
Wilmington, DE 19807 (US)

(72) Inventor:
  • HOBBS, Frank, W.
    Wilmington, DE 19803 (US)

(74) Representative: Jones, Alan John et al
CARPMAELS & RANSFORD 43 Bloomsbury Square
London, WC1A 2RA
London, WC1A 2RA (GB)

   


(54) AMINO-THIO-ACRYLONITRILES AS MEK INHIBITORS