(19)
(11) EP 1 165 059 A1

(12)

(43) Date of publication:
02.01.2002 Bulletin 2002/01

(21) Application number: 00916329.6

(22) Date of filing: 14.03.2000
(51) International Patent Classification (IPC)7A61K 31/08, A61K 31/10, C07K 7/06, C07K 7/08
(86) International application number:
PCT/US0006/667
(87) International publication number:
WO 0054/770 (21.09.2000 Gazette 2000/38)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 15.03.1999 US 268274
17.11.1999 US 442099

(71) Applicants:
  • Boston Life Sciences, Inc.
    Boston, Massachusetts 02116 (US)
  • Children's Medical Center Corporation
    Cambridge, MA 02115 (US)

(72) Inventors:
  • THORN, Richard, M.
    North Easton, MA 02356 (US)
  • LANSER, Marc, E.
    Dover, MA 02030 (US)
  • MOSES, Marsha, A.
    Brookline, MA 02146 (US)
  • WIEDERSCHAIN, Dmitri, G.
    Brookline, MA 02146 (US)

(74) Representative: Horner, Martin Grenville et al
Cruikshank & Fairweather 19 Royal Exchange Square
Glasgow G1 3AE, Scotland
Glasgow G1 3AE, Scotland (GB)

   


(54) PHARMACEUTICAL COMPOSITIONS COMPRISING TROPONIN SUBUNITS, FRAGMENTS AND HOMOLOGS THEREOF AND METHODS OF THEIR USE TO INHIBIT ANGIOGENESIS