(19)

(11)

EP 1 165 116 A1

(12)

(43) Date of publication: 02.01.2002 Bulletin 2002/01 (21) Application number: 00918469.8 (22) Date of filing: 28.03.2000

(51) International Patent Classification (IPC)7: A61K 38/17, A61K 38/19 (86) International application number: PCT/US0008/161 (87) International publication number: WO 0059/530 (12.10.2000 Gazette 2000/41)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 02.04.1999 US 127588 P (71) Applicant: IMMUNEX CORPORATION Seattle Washington 98101 (US)	(72) Inventor: HAYES, F., Ann Seattle, WA 98144 (US) (74) Representative: Dörries, Hans Ulrich, Dr.  Dörries, Frank-Molnia & Pohlman, Triftstrasse 13 80538 München 80538 München (DE)