(19)
(11) EP 1 165 185 A2

(12)

(88) Date of publication A3:
04.01.2001

(43) Date of publication:
02.01.2002 Bulletin 2002/01

(21) Application number: 00916583.8

(22) Date of filing: 22.03.2000
(51) International Patent Classification (IPC)7: A61P 37/00, A61P 35/00, A61K 39/395, A61K 38/17, A61K 45/06
// A61K48:00, A61K39:395, A61K38:17, A61K39:395, A61K38:14, A61K39:395, A61K38:04, A61K39:395, A61K31:00
(86) International application number:
PCT/US0007/521
(87) International publication number:
WO 0056/405 (28.09.2000 Gazette 2000/39)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 22.03.1999 US 125683 P
26.03.1999 US 126522 P
20.05.1999 US 135169 P
06.08.1999 US 147383 P

(71) Applicant: Human Genome Sciences, Inc.
Rockville, MD 20850 (US)

(72) Inventors:
  • NI, Jian
    Rockville, MD 20853 (US)
  • ROSEN, Craig, A.
    Laytonsville, MD 20882 (US)
  • GENTZ, Reiner L.
    Rockville, MD 20850 (US)

(74) Representative: VOSSIUS & PARTNER 
Siebertstrasse 4
81675 München
81675 München (DE)

   


(54) HUMAN TUMOR NECROSIS FACTOR RECEPTOR-LIKE 2