(19)

(11)

EP 1 165 222 A1

(12)

(43) Date of publication: 02.01.2002 Bulletin 2002/01 (21) Application number: 00910145.2 (22) Date of filing: 10.02.2000

(51) International Patent Classification (IPC)7: B01F 17/00 (86) International application number: PCT/US0003/523 (87) International publication number: WO 0047/031 (17.08.2000 Gazette 2000/33)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 10.02.1999 US 119404 P (71) Applicant: UNIVERSITY OF PITTSBURGH Pittsburgh, Pennsylvania 15260 (US)	(72) Inventors: WILCOX, Craig, Stephens Pittsburgh, PA 15206 (US) YANG, Jaemoon Pittsburgh, PA 15213 (US) (74) Representative: Nash, David Allan  Haseltine Lake & Co., Imperial House, 15-19 Kingsway London WC2B 6UD London WC2B 6UD (GB)