INHIBITORS OF LFA-1 BINDING TO ICAMs AND USES THEREOF - Patent 1165504

(19)

(11)

EP 1 165 504 A2

(12)

(88)	Date of publication A3:
	09.08.2001

(43)	Date of publication:
	02.01.2002 Bulletin 2002/01

(21)	Application number: 00921626.8

(22)	Date of filing: 03.04.2000

(51)	International Patent Classification (IPC)⁷: C07C 323/37, C07C 323/09, C07D 213/70, C07D 295/12, C07D 215/36, C07C 323/41, C07D 235/06, C07C 323/32, C07C 323/65, A61K 31/135, A61K 31/04

(86)	International application number:
	PCT/US0008/840

(87)	International publication number:
	WO 0059/878 (12.10.2000 Gazette 2000/41)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

(30)

Priority:

02.04.1999 US 285325

(71)	Applicant: ICOS CORPORATION
	Bothell, WA 98021 (US)

(72)	Inventors:
	FOWLER, Kerry Seattle, WA 98103 (US) ORME, Mark Seattle, WA 98103 (US) STAUNTON, Donald, E. Kirkland, WA 98033 (US) ADOLPHSON, Janet Moonlake Terrace, WA 98043 (US)

(74)	Representative: Helbing, Jörg, Dr. Dipl.-Chem. et al
	Patentanwälte von Kreisler-Selting-Werner, Postfach 10 22 41 50462 Köln 50462 Köln (DE)

(54)	INHIBITORS OF LFA-1 BINDING TO ICAMs AND USES THEREOF