(19)
(11) EP 1 165 522 A1

(12)

(43) Date of publication:
02.01.2002 Bulletin 2002/01

(21) Application number: 00921705.0

(22) Date of filing: 05.04.2000
(51) International Patent Classification (IPC)7C07D 239/48, C07D 239/46, A61K 31/506, A61P 25/00
(86) International application number:
PCT/US0009/004
(87) International publication number:
WO 0059/893 (12.10.2000 Gazette 2000/41)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 06.04.1999 US 127923 P
12.04.1999 US 128842 P

(71) Applicant: Krenitsky Pharmaceutical Inc
Durham, NC 27707 (US)

(72) Inventors:
  • KELLEY, James, L.
    Raleigh, NC 27614 (US)
  • KRENITSKY, Thomas, A.
    Chapel Hill, NC 27514 (US)
  • BEAUCHAMP, Lilia, M.
    Raleigh, NC 27607 (US)

(74) Representative: MacDougall, Donald Carmichael et al
Cruikshank & Fairweather 19 Royal Exchange Square
Glasgow G1 3AE, Scotland
Glasgow G1 3AE, Scotland (GB)

   


(54) NEUROTROPHIC THIO SUBSTITUTED PYRIMIDINES