(19)
(11) EP 1 165 787 A2

(12)

(88) Date of publication A3:
25.01.2001

(43) Date of publication:
02.01.2002 Bulletin 2002/01

(21) Application number: 00919964.7

(22) Date of filing: 31.03.2000
(51) International Patent Classification (IPC)7C12N 15/12, C12N 15/11, C12Q 1/02, C12Q 1/68, C07K 16/18, G01N 33/68
(86) International application number:
PCT/US0008/592
(87) International publication number:
WO 0058/472 (05.10.2000 Gazette 2000/40)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 31.03.1999 US 127261 P
22.11.1999 US 166927 P

(71) Applicant: The University of North Carolina at Chapel Hill
Chapel Hill, NC 27599-4105 (US)

(72) Inventors:
  • XIONG, Yue
    Chapel Hill, NC 27514 (US)
  • OHTA, Tomohiko
    Tokyo 155-0032 (JP)

(74) Representative: Horner, Martin Grenville et al
Cruikshank & Fairweather 19 Royal Exchange Square
Glasgow G1 3AE, Scotland
Glasgow G1 3AE, Scotland (GB)

   


(54) ISOLATED DNA ENCODING CULLIN REGULATORS ROC1 AND ROC2, ISOLATED PROTEINS ENCODED BY THE SAME, AND METHODS UTILIZING THE SAME