(19)
(11) EP 1 168 919 A2

(12)

(88) Date of publication A3:
11.10.2001

(43) Date of publication:
09.01.2002 Bulletin 2002/02

(21) Application number: 00919668.4

(22) Date of filing: 24.03.2000
(51) International Patent Classification (IPC)7: A01N 43/04, A61K 31/70, C12Q 1/68, C07H 21/02, C07H 21/04, C07H 19/20
(86) International application number:
PCT/US0008/020
(87) International publication number:
WO 0062/736 (26.10.2000 Gazette 2000/43)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 06.04.1999 US 127958 P

(71) Applicants:
  • East Carolina University
    Greenville, NC 27858-4353 (US)
  • Nyce, Jonathan W.
    Princeton, NY 08540 (US)

(72) Inventor:
  • NYCE, Jonathan, W.
    Princeton, NJ 08540 (US)

(74) Representative: Becker Kurig Straus 
Patentanwälte Bavariastrasse 7
80336 München
80336 München (DE)

   


(54) LOW ADENOSINE ANTI-SENSE OLIGONUCLEOTIDE, COMPOSITIONS, KIT AND METHOD FOR TREATMENT OF AIRWAY DISORDERS ASSOCIATED WITH BRONCHOCONSTRICTION, LUNG INFLAMMATION, ALLERGY(IES) AND SURFACTANT DEPLETION