(19)
(11) EP 1 169 049 A2

(12)

(88) Date of publication A3:
11.01.2001

(43) Date of publication:
09.01.2002 Bulletin 2002/02

(21) Application number: 00921764.7

(22) Date of filing: 07.04.2000
(51) International Patent Classification (IPC)7A61K 38/04, A61K 31/40, A61K 31/166, A61P 19/08
(86) International application number:
PCT/US0009/121
(87) International publication number:
WO 0061/167 (19.10.2000 Gazette 2000/42)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 09.04.1999 US 289229

(71) Applicant: Osteoscreen, Inc.
San Antonio, TX 78229 (US)

(72) Inventor:
  • Mundy, Gregory R.
    San Antonio, TX 78229 (US)

(74) Representative: Sexton, Jane Helen et al
J.A. KEMP & CO. 14 South Square Gray's Inn
London WC1R 5JJ
London WC1R 5JJ (GB)

   


(54) TREATMENT OF MYELOMA BONE DISEASE WITH PROTEASOMAL AND NF-KAPPA-B ACTIVITY INHIBITORS