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(11)

EP 1 169 061 A1

(12)

(43) Date of publication: 09.01.2002 Bulletin 2002/02 (21) Application number: 99912458.9 (22) Date of filing: 12.03.1999

(51) International Patent Classification (IPC)7: A61K 45/06, A61K 31/535, A61K 31/557, A61K 31/495, A61K 31/135, A61K 31/445, A61P 27/06 (86) International application number: PCT/US9905/423 (87) International publication number: WO 0054/810 (21.09.2000 Gazette 2000/38)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (71) Applicant: ALCON LABORATORIES, INC. Fort Worth Texas 76134-2099 (US)	(72) Inventor: DESANTIS, Louis, Jr. Fort Worth, TX 76109 (US) (74) Representative: Wain, Christopher Paul et al A.A. Thornton & Co. 235 High Holborn London WC1V 7LE London WC1V 7LE (GB)