(19)
(11) EP 1 169 457 A2

(12)

(88) Date of publication A3:
04.01.2001

(43) Date of publication:
09.01.2002 Bulletin 2002/02

(21) Application number: 00920058.5

(22) Date of filing: 31.03.2000
(51) International Patent Classification (IPC)7C12N 15/45, C12N 7/04, C07K 14/135, A61K 39/155
(86) International application number:
PCT/US0008/802
(87) International publication number:
WO 0061/611 (19.10.2000 Gazette 2000/42)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 13.04.1999 US 291894

(71) Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE DEPARTMENT OF HEALTH & HUMAN SERVICES
Rockville, MD 20852 (US)

(72) Inventors:
  • COLLINS, Peter, L.
    Rockville, MD 20852 (US)
  • MURPHY, Brian, R.
    Bethesda, MD 20861 (US)
  • WHITEHEAD, Stephen, S.
    Gaithersburg, MD 20878 (US)

(74) Representative: Suèr, Steven Johannes et al
Ablett & Stebbing, Caparo House, 101-103 Baker Street
London W1M 1FD
London W1M 1FD (GB)

   


(54) PRODUCTION OF ATTENUATED CHIMERIC RESPIRATORY SYNCYTIAL VIRUS VACCINES FROM CLONED NUCLEOTIDE SEQUENCES