(19)

(11)

EP 1 169 649 A2

(12)

(88) Date of publication A3: 08.03.2001 (43) Date of publication: 09.01.2002 Bulletin 2002/02 (21) Application number: 00923395.8 (22) Date of filing: 14.04.2000

(51) International Patent Classification (IPC)7: G01N 33/68, B01J 19/00 (86) International application number: PCT/US0010/171 (87) International publication number: WO 0063/701 (26.10.2000 Gazette 2000/43)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 15.04.1999 US 129449 P (71) Applicant: The Board of Trustees of The Leland Stanford Junior University Palo Alto, CA 93404-1850 (US)	(72) Inventors: BROWN, Patrick Stanford, CA 94305 (US) HAAB, Brian Berkeley, CA 94703 (US) (74) Representative: Brasnett, Adrian Hugh et al Mewburn Ellis York House 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)