(19)
(11) EP 1 171 623 A2

(12)

(88) Date of publication A3:
23.08.2001

(43) Date of publication:
16.01.2002 Bulletin 2002/03

(21) Application number: 00922075.7

(22) Date of filing: 12.04.2000
(51) International Patent Classification (IPC)7C12N 15/86
(86) International application number:
PCT/US0009/695
(87) International publication number:
WO 0061/737 (19.10.2000 Gazette 2000/42)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 13.04.1999 US 129006 P

(71) Applicant: The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services
Bethesda, MD 20852 (US)

(72) Inventors:
  • MURPHY, Brian, R.
    Bethesda, MD 20816 (US)
  • COLLINS, Peter, L.
    Rockville, MD 20852 (US)
  • DURBIN, Anna, P.
    Takoma Park, MD 20912 (US)
  • SKIADOPOULOS, Mario, H.
    Potomac, MD 20854 (US)

(74) Representative: Suèr, Steven Johannes et al
Ablett & Stebbing, Caparo House, 101-103 Baker Street
London W1M 1FD
London W1M 1FD (GB)

   


(54) PRODUCTION OF ATTENUATED NEGATIVE STRANDED RNA VIRUS VACCINES