(19)

(11)

EP 1 173 429 A1

(12)

(43) Date of publication: 23.01.2002 Bulletin 2002/04 (21) Application number: 00920078.3 (22) Date of filing: 31.03.2000

(51) International Patent Classification (IPC)7: C07D 295/092, C07D 321/12, C07D 453/02 (86) International application number: PCT/US0008/833 (87) International publication number: WO 0058/296 (05.10.2000 Gazette 2000/40)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 31.03.1999 US 127250 P (71) Applicant: SmithKline Beecham Corporation Philadelphia, PA 19103 (US)	(72) Inventor: YAMASHITA, Dennis, S. Wayne, PA 19087 (US) (74) Representative: Rutter, Keith  GlaxoSmithKline, Two New Horizons Court Brentford, Middlesex TW8 9EP Brentford, Middlesex TW8 9EP (GB)