(19)
(11) EP 1 173 438 A1

(12)

(43) Date of publication:
23.01.2002 Bulletin 2002/04

(21) Application number: 00918714.7

(22) Date of filing: 13.04.2000
(51) International Patent Classification (IPC)7C07D 471/04, C07D 487/04, A61K 31/437, A61K 31/4188
(86) International application number:
PCT/DK0000/179
(87) International publication number:
WO 0063/208 (26.10.2000 Gazette 2000/43)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 16.04.1999 DK 50899
22.09.1999 DK 134599
12.01.2000 DK 200000042

(71) Applicants:
  • NOVO NORDISK A/S
    2880 Bagsvaerd (DK)
  • Boehringer Ingelheim International GmbH
    55216 Ingelheim am Rhein (DE)

(72) Inventors:
  • DÖRWALD, Florencio, Zaragoza
    DK-2750 Ballerup (DK)
  • ANDERSEN, Knud, Erik
    DK-2605 Br ndby (DK)
  • JORGENSEN, Tine, Krogh
    DK-3650 lstykke (DK)
  • PESCHKE, Bernd
    DK-2760 M l v (DK)
  • WULFF, Birgitte, Schjellerup
    DK-2830 Virum (DK)
  • PETTERSSON, Ingrid
    DK-1864 Frederiksberg (DK)
  • RUDOLF, Klaus
    D-88447 Warthausen (DE)
  • STENKAMP, Dirk
    D-88400 Biberach (DE)
  • HURNAUS, Rudolf
    D-88400 Biberach (DE)
  • MÜLLER, Stephan, Georg
    D-88447 Warthausen (DE)
  • KRIST, Bernd
    D-89047 Ulm (DE)

(74) Representative: Stephensen, Birgitte Borregaard (DK) 
c/o Novo Nordisk A/S Corporate Patents Novo Allé
2880 Bagsvaerd
2880 Bagsvaerd (DK)

   


(54) SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE