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(11)

EP 1 173 566 A2

(12)

(88) Date of publication A3: 15.02.2001 (43) Date of publication: 23.01.2002 Bulletin 2002/04 (21) Application number: 00926278.3 (22) Date of filing: 20.04.2000

(51) International Patent Classification (IPC)7: C12N 15/12, C07K 14/705, C07K 16/28, C12Q 1/68, A61K 38/17, G01N 33/53 (86) International application number: PCT/US0010/884 (87) International publication number: WO 0065/054 (02.11.2000 Gazette 2000/44)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 23.04.1999 US 130694 P 23.06.1999 US 140580 P (71) Applicant: Incyte Genomics, Inc. Palo Alto, CA 94304 (US)

(72) Inventors: HILLMAN, Jennifer, L. Mountain View, CA 94040 (US) BANDMAN, Olga Mountain View, CA 94043 (US) TANG, Y., Tom San Jose, CA 95118 (US) LAL, Preeti Santa Clara, CA 95054 (US) YUE, Henry Sunnyvale, CA 94087 (US) REDDY, Roopa Sunnyvale, CA 94086 (US) AZIMZAI, Yalda Hayward, CA 94545 (US) BAUGHN, Mariah, R. San Leandro, CA 94577 (US) (74) Representative: Wright, Simon Mark  J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)