(19)

(11)

EP 1 175 236 A1

(12)

(43) Date of publication: 30.01.2002 Bulletin 2002/05 (21) Application number: 00931951.8 (22) Date of filing: 21.04.2000

(51) International Patent Classification (IPC)7: A61L 31/02, A61L 31/08, A61L 31/12 (86) International application number: PCT/US0011/092 (87) International publication number: WO 0064/506 (02.11.2000 Gazette 2000/44)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 23.04.1999 US 298545 (71) Applicant: Agion Technologies, L.L.C. Wakefield, MA 01880 (US)	(72) Inventors: BARRY, John, E. Derry, NH 03038 (US) TROGOLO, Jeffrey, A. Boston, MA 02116 (US) (74) Representative: Wibbelmann, Jobst, Dr., Dipl.-Chem. et al Wuesthoff & Wuesthoff, Patent- und Rechtsanwälte, Schweigerstrasse 2 81541 München 81541 München (DE)