(19)

(11)

EP 1 178 788 A1

(12)

(43) Date of publication: 13.02.2002 Bulletin 2002/07 (21) Application number: 99924332.2 (22) Date of filing: 18.05.1999

(51) International Patent Classification (IPC)7: A61K 31/05, A61K 31/09, A61K 31/19, C07C 59/48, C07C 43/205, C07C 43/215, C07C 39/06, C07C 39/215 (86) International application number: PCT/US9911/001 (87) International publication number: WO 0069/430 (23.11.2000 Gazette 2000/47)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (71) Applicant: Calyx Therapeutics, Inc. Hayward, CA 94545 (US)	(72) Inventors: Nag, Bishwajit Fremont, CA 94555 (US) Medicherla, Satyanarayana Cupertino, CA 95014 (US) Dey, Debendranath Union City, CA 94587 (US) (74) Representative: Lipscombe, Martin John et al Keith W Nash & Co, Pearl Assurance House, 90-92 Regent Street Cambridge CB2 1DP Cambridge CB2 1DP (GB)