(19)
(11) EP 1 179 020 A1

(12)

(43) Date of publication:
13.02.2002 Bulletin 2002/07

(21) Application number: 00932180.3

(22) Date of filing: 08.05.2000
(51) International Patent Classification (IPC)7C07K 14/545, A61K 38/20
(86) International application number:
PCT/US0012/565
(87) International publication number:
WO 0068/267 (16.11.2000 Gazette 2000/46)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 06.05.1999 US 132855 P

(71) Applicant: THE SCHEPENS EYE RESEARCH INSTITUTE, INC.
Boston, MA 02114 (US)

(72) Inventors:
  • KLASSEN, Henry
    Newport Beach, CA 92662 (US)
  • WHITELEY, Simon, J.
    Arlington, MA 02174 (US)
  • YOUNG, Michael, J.
    Gloucester, MA 01930 (US)

(74) Representative: Hofstetter, Alfons J., Dr.rer.nat. et al
Hofstetter, Schurack & Skora Balanstrasse 57
81541 München
81541 München (DE)

   


(54) LOW-DOSE IL-1BETA-INDUCED PHOTORECEPTOR CELL RESCUE WITHOUT RETINAL DYSPLASIA