(19)
(11) EP 1 179 062 A2

(12)

(88) Date of publication A3:
15.02.2001

(43) Date of publication:
13.02.2002 Bulletin 2002/07

(21) Application number: 00930723.2

(22) Date of filing: 12.05.2000
(51) International Patent Classification (IPC)7C12N 15/12, C07K 14/47, C12N 1/21, A61K 38/00, A61K 39/00
(86) International application number:
PCT/US0013/248
(87) International publication number:
WO 0068/384 (16.11.2000 Gazette 2000/46)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 12.05.1999 US 133783 P

(71) Applicant: Xencor, Inc.
Pasadena, CA 91107-3708 (US)

(72) Inventor:
  • FIEBIG, Klaus
    D-60313 Frankfurt (DE)

(74) Representative: Kiddle, Simon John et al
Mewburn Ellis, York House, 23 Kingsway
London WC2B 6HP
London WC2B 6HP (GB)

   


(54) NUCLEIC ACIDS AND PROTEINS WITH P53 ACTIVITY AND ALTERED TETRAMERIZATION DOMAINS