(19)

(11)

EP 1 179 075 A2

(12)

(88) Date of publication A3: 08.03.2001 (43) Date of publication: 13.02.2002 Bulletin 2002/07 (21) Application number: 00935942.3 (22) Date of filing: 12.05.2000

(51) International Patent Classification (IPC)7: C12N 15/56, C12N 9/24, C12N 1/21, D21C 9/10 (86) International application number: PCT/US0013/172 (87) International publication number: WO 0068/396 (16.11.2000 Gazette 2000/46)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 12.05.1999 US 133714 P (71) Applicant: Xencor, Inc. Pasadena, CA 91107-3708 (US)	(72) Inventor: BENTZIEN, Joerg, M. Pasdena, CA 91101 (US) (74) Representative: Kiddle, Simon John et al Mewburn Ellis, York House, 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)