(19)
(11) EP 1 179 083 A1

(12)

(43) Date of publication:
13.02.2002 Bulletin 2002/07

(21) Application number: 00923545.8

(22) Date of filing: 21.04.2000
(51) International Patent Classification (IPC)7C12N 15/864, C12N 15/867, C12N 15/869, C12N 15/63, C12N 15/64, C12N 5/10, C12N 15/38, A61K 48/00
(86) International application number:
PCT/US0010/669
(87) International publication number:
WO 0065/077 (02.11.2000 Gazette 2000/44)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 22.04.1999 US 130551 P

(71) Applicant: THE GENERAL HOSPITAL CORPORATION
Boston, MA 02114 (US)

(72) Inventors:
  • SENA-ESTEVES, Miguel
    Philadelphia, PA 19147 (US)
  • BREAKEFIELD, Xandra, O.
    Newton, MA 02159 (US)
  • SAEKI, Yoshinaga
    Toyama,Toyama 939-8015 (JP)

(74) Representative: Chapman, Paul William et al
Kilburn & Strode, 20 Red Lion Street
London WC1R 4PJ
London WC1R 4PJ (GB)

   


(54) TRIPLE HYBRID AMPLICON VECTOR SYSTEMS TO GENERATE RETROVIRAL PACKAGING LINES