(19)

(11)

EP 1 180 144 A2

(12)

(88) Date of publication A3: 05.04.2001 (43) Date of publication: 20.02.2002 Bulletin 2002/08 (21) Application number: 00939403.2 (22) Date of filing: 26.05.2000

(51) International Patent Classification (IPC)7: C12N 15/12, C07K 14/47, C12Q 1/68, C12N 5/10, A61K 38/17, G01N 33/50, G01N 33/68, C07K 16/18, A01K 67/027 (86) International application number: PCT/US0014/826 (87) International publication number: WO 0073/450 (07.12.2000 Gazette 2000/49)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 27.05.1999 US 136652 P (71) Applicant: Incyte Genomics, Inc. Palo Alto, CA 94304 (US)	(72) Inventors: TANG, Y., Tom San Jose, CA 95118 (US) YUE, Henry Sunnyvale, CA 94304 (US) HILLMAN, Jennifer, L. Mountain View, CA 94040 (US) BAUGHN, Mariah, R. San Leandro, CA 94577 (US) TRAN, Bao Santa Clara, CA 95051 (US) AZIMZAI, Yalda Castro Valley, CA 94552 (US) (74) Representative: Wright, Simon Mark  J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)