(19)

(11)

EP 1 180 147 A1

(12)

(43) Date of publication: 20.02.2002 Bulletin 2002/08 (21) Application number: 00939397.6 (22) Date of filing: 26.05.2000

(51) International Patent Classification (IPC)7: C12N 15/19, C07K 14/52, C07K 16/24, C12N 15/62, G01N 33/68, C12N 5/10 (86) International application number: PCT/US0014/795 (87) International publication number: WO 0073/458 (07.12.2000 Gazette 2000/49)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 28.05.1999 US 136485 P (71) Applicant: ZymoGenetics, Inc. Seattle, WA 98102 (US)	(72) Inventor: CONKLIN, Darrell, C. Seattle, WA 98102 (US) (74) Representative: Schlich, George William et al Mathys & Squire European Patent Attorneys, 100 Gray's Inn Road London WC1X 8AL London WC1X 8AL (GB)